Problem & Solution
In osteoarthritis of the knee, the progressive loss of cartilage can be estimated by measuring the surrogate of minimum joint space width (mJSW) narrowing of the medial compartment on an x-ray image.
Standardized protocols minimize variation in acquiring radiographic images, and computerized measurement is used to improve reproducibility. Other surrogate measurements across the knee joint may provide improved clinical measures with increased precision and greater sensitivity to OA so that clinical trials of potential therapies can be performed more quickly and with fewer patients.
Improve sensitivity when measuring disease progression
Optasia Medical have developed a unique software workflow solution to efficiently and comprehensively annotate knee anatomy. KneeToolTM provides rapid, accurate and reproducible assessment of the accepted standard (mJSW), while simultaneously providing novel, potentially more sensitive methods of measuring disease progression. The software employs a proprietary statistical model-based image analysis technique, which uses a manual 6-point initialisation to then automatically segment the femoral and tibial margins of the knee joint space.