"Finding new and improved methods of measuring osteoarthritis is extremely important to us, as well as the wider medical community. Optasia Medical's software allows us to fully interrogate knee x-ray images for evidence of disease progression"
Karen Maunder
Clinical Development Manager
Procter & Gamble Pharmaceuticals, Italy
Osteoarthritis

Optasia Medical and Osteoarthritis

Knee osteoarthritis (OA) is a slow progressive disease characterized by loss of cartilage in the joint, leading to reduced movement and increased pain. Longitudinal evaluation of the disease relies on a mix of clinical and radiographic features — chiefly pain, disability and structural changes.

The progressive loss of cartilage can be estimated by measuring the surrogate of minimum joint space width (mJSW) narrowing of the medial compartment of the knee on an x-ray image. This method of measurement, however, may mask an effect in the whole joint. Better surrogate measurements across the knee joint may provide improved clinical measures with greater sensitivity to OA so that clinical trials of potential therapies can be performed more quickly with fewer patients.

Optasia Medical has developed a unique software solution — KneeAnalyzerTM — that automatically annotates a large proportion of the key anatomy of the knee, dramatically reducing the time taken to analyze these images. Additionally, KneeAnalyzer aids the user in exploring both current and potentially more efficient methods of measuring osteoarthritis progression. In summary, the measurements made automatically are the:

  • mJSW in either compartment;
  • JSW at any position in the medial or lateral compartment;
  • Area defined by either compartment;
  • Difference in shape between baseline and follow up images.

Learn how Optasia Medical's commitment to innovation can aid in more accurate evaluation and more effective treatment of osteoarthritis.

Case Study coming soon...